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diagnosis rheumatology differential lupus causes management systemic alopecia classification dermatology diffuse hairloss vasculitis criteria focal hematology nephrology arthropathies arthropathy champs
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Systemic Lupus Erythematosus ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... anti-Smith Ab, low complements ... RNP antibodies, Complement ... : Drug induced SLE ... • Kidney biopsy
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... are evocative of SLE ... 80% - Low complement ... lupus #Systemic #Erythematosus
Systemic Lupus Erythematosus (SLE): Pathogenesis • Genetic factors (Mutations in HLA- DR2/HLA-DR3 genes, complement genes, cytokine
Systemic Lupus Erythematosus ... (SLE): Pathogenesis ... HLA-DR3 genes, complement ... Systemic #Lupus #Erythematosus ... #SLE #Pathophysiology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Systemic Lupus Erythematosus ... anticoagulant - Low complement ... #Rheumatology #SLE ... #Lupus #Erythematosus
Approach to managing Glomerulonephritis (GN) in children. ANCA, antineutrophil cytoplasmic antibodies; c-ANCA, cytoplasmic antineutrophil cytoplasmic antibodies;
cytoplasmic antibodies; SLE ... systemic lupus erythematosus ... Glomerulonephritis #Algorithm
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Differential Diagnosis Algorithm ... Systemic Lupus Erythematosus ... Lymphocytes on Biopsy ... Reed-Sternberg Cells on Biopsy ... Differential #Diagnosis #Algorithm
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... 90% - Low complement ... Systemic Lupus Erythematosus ... are evocative of SLE ... 80% - Low complement
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Differential Diagnosis Algorithm ... - Irreversible-biopsy ... required • Lupus erythematosus ... - Irreversible-biopsy ... Discoid lupus erythematosus
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Systemic Lupus Erythematosus ... anticoagulant • Complement ... Classification #Criteria #SLE ... Systemic #Lupus #Erythematosus
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