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diagnosis differential hypokalemia rheumatology hyperkalemia hyponatremia lupus management neurology potassium workup alkalosis metabolic vasculitis chloride classification druginduced glomerular glomerulonephritis hematology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
in >90% - Low ... complement - Rare ... Discontinuation of causal ... 60-80% - Low ... complement - 50
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low ... Complement: Post-strep ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... are evocative of SLE ... Positive in 60-80% of cases ... 60-80% - Low ... complement - 50
Causes of Hypernatremia - Differential Diagnosis Algorithm Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L High
Causes of Hypernatremia ... Osmotic diuresis (see ... mannitol, glucosuria Low ... Hypernatremia #Nephrology ... #Causes
The Diagnostic Approach to Hyperkalemia Drugs - Amiloride - Spironolactone - Triamterene - Trimethoprim - Pentamidine -
inhibitors Other causes ... transplant - SLE ... Ketoconazole Low ... #Hyperkalemia #Algorithm ... #differential #causes
Causes of Hypokalemia - Differential Diagnosis Algorithm Once pseudohypokalemia is ruled out, causes of hypokalemia can be
Causes of Hypokalemia ... Differential Diagnosis Algorithm ... filling of bucket (low ... Differential #Diagnosis #Algorithm ... #nephrology
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... Normal Acid-Base: Low ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #low #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted - 2° hyperaldosteronism • Low Urine Cl-: Vomiting,
Differential Diagnosis Algorithm ... hyperaldosteronism • Low ... , NGT suction, Low ... Differential #Diagnosis #Algorithm ... #Nephrology #Causes
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... Differential Diagnosis Algorithm ... (MPA) • SLE ... #Proteinuria #Nephrology ... #Causes
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