55 results
differential causes hematology workup neurology management pulmonary disease hemolytic obgyn rheumatology dyspnea obstetrics pathophysiology autoimmune chronic deficiency dermatology disorders erythematosus
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Warm vs Cold Autoimmune ... Mechanism: IgG and Complement-mediated ... Mechanism: IgM and Complement-mediated ... BostonChiefs #Warm #Cold ... #hematology #diagnosis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... • Symptoms of anemia ... anemia • Cold ... Positive Coombs testing ... temperatures by fixing complement
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential Diagnosis ... Algorithm Extravascular ... Warm AIHA • Cold ... perfringens - Complement-Mediated ... immune-complex hemolytic anemia
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Algorithm • Sickle ... Agglutination - Cold ... cardiac valve, vasculitis ... #hematology #testing
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... Differential Diagnosis ... against MPO • Complement
Vascular Joint Pain - Differential Diagnosis Algorithm - Constant Pain (Ischemia) - Acute Onset -
- Differential Diagnosis ... Algorithm - ... Claudication) - Cold ... • Sickle Cell Anemia ... #Differential #Diagnosis
Pulmonary Function Testing (PFT) Interpretation Algorithm Restrictive Lung Disease: • Chest wall or neuromuscular disorders • Interstitial
Pulmonary Function Testing ... Interpretation Algorithm ... Pulmonary #Function #Testing ... Interpretation #Algorithm ... #diagnosis #asthma
Pulmonary Function Tests (PFTs) - Interpretation Algorithm • Normal • Pulmonary Hypertension, Anemia, Carboxyhemoglobinemia • Chest
Interpretation Algorithm ... Hypertension, Anemia ... Emphysematous COPD ... Interpretation #Algorithm ... #diagnosis
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
patients < 50 yrs old ... - Normocytic Anemia ... palpation - Vasculitic ... Pathophysiology #Diagnosis ... Signs #Symptoms #Vasculitis
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... Glomerulonephritis #Vasculitis ... #differential #diagnosis ... #algorithm #rheumatology
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