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diagnosis differential hyponatremia sodium causes glomerular glomerulonephritis hematology nephrotic acute aki anemia blood disease gammopathy hematuria hemolytic hypernatremia hypotonic initial
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Post-strep GN, Lupus Nephritis ... Idiopathic • Normal Complement ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... for ANCA-related vasculitis ... #workup #diagnosis ... #nephritic #nephrology
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup ... and Diagnosis Algorithm ... mimics, repeat testing ... → Refer to Nephrology ... #Workup #urology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... Algorithm and Differential ... Glomerulonephritis / Vasculits ... • Interstitial nephritis ... #Diagnosis #nephrology
Hypernatremia Diagnosis and Workup Step 1 . Repeat the sodium concentration. Step 2. Check plasma osmolality. NORMAL PLASMA
Diagnosis and Workup ... liver failure • nephrotic ... Hypernatremia #Diagnosis #Workup ... #Algorithm #Nephrology
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... for ANCA-related vasculitis ... glomerular #disease #workup ... #nephrology #nephrotic
Modified Hyponatremia Algorithm Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants Hypotonic Hyponatremia: • ADH ON (UOsm > 100):
Modified Hyponatremia Algorithm ... failure, Cirrhosis, Nephrotic ... Cerebral salt wasting ... #Hyponatremia #Algorithm ... diagnosis #sodium #nephrology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... cardiac valve, vasculitis ... Differential #Diagnosis #Algorithm ... #workup #hematology ... #testing
Causes of Hyponatremia - Differential Diagnosis Algorithm Hypovolemia, UNa > 20: • Renal losses, Diuretic excess,
Differential Diagnosis Algorithm ... Cerebral salt wasting ... , UNa < 20 • Nephrotic ... Differential #Diagnosis #Algorithm ... #Causes #nephrology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... hematology for workup ... Rheumatologic, Vasculitides ... disease, Kawasaki, Nephrotic ... Differential #Diagnosis #Algorithm
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