10 results
diagnosis differential nephrology acute aki rheumatology injury gammopathy glomerulonephritis hepatology hepatorenal igg4 kidneyinjury management mgrs monoclonal rapidly renal rpgn significance
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Rapidly Progressive ... pathophysiologic causes ... • Limited to Kidney ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
proteinuria, rapidly progressing ... tract, and often causes ... Kidneys -> glomerulonephritis ... against MPO • Complement ... #rheumatology #classification
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... Distributive Shock, HRS ... Emboli, Thrombosis, Vasculitis ... Diagnosis #nephrology #causes ... #algorithm
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Acute Kidney Injury ... - Classification ... - Small vessel vasculitis ... - TTP/HUS ... tubular necrosis (causes
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Kidney Injury (AKI ... Differential Diagnosis Algorithm ... Acute Kidney Injury ... Malignancy Rapidly Progressive ... #Causes
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
• ESR > 50mm/hr ... musculoskeletal systems • Kidneys ... tract, and often causes ... Elevated AST ALT • Hypocomplementemia ... ) • Hypocomplementemic
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
Hepatorenal Syndrome (HRS ... • Caused by splanchnic ... No structural kidney ... Classification: ... Type 1): • Rapid progression
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... osmolarity If cause ... Glomerulonephritis / Vasculits ... pressure • TTP / HUS
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
disease caused ... guide subtype classification ... tubulopathy) - Complement ... formation causing vasculitis ... function and prevent progression
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
inflammation -> progressive ... aortitis, mimics vasculitis ... • Kidneys: Tubulointerstitial ... - ↑ IgE, ↓ complement ... • Classification
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