16 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... CHAMPS #Mnemonic #diagnosis
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
pseudotumor 4 phenotypes ... with response to treatment ... rheumatoid factor), ± hypocomplementemia ... #management #phenotypes ... #workup #treatment
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Mechanism: IgG and Complement-mediated ... Spherocytes • Treatment ... Mechanism: IgM and Complement-mediated ... transient hemolysis • Treatment ... #hematology #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... Differential Diagnosis ... against MPO • Complement
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
- Differential Diagnosis ... Algorithm Extravascular ... perfringens - Complement-Mediated ... immune-complex hemolytic anemia ... #Algorithm #Causes
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... Algorithm • Sickle ... disease (diverse genotypes ... #Algorithm #workup
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential Diagnosis ... Algorithm Spurious ... effect following treatment ... Iron deficiency anemia ... #Algorithm #Causes
Visceral Leishmaniasis - Diagnosis and Management Summary
Species: Leishmania donovani, Leishmania infantum, Leishmania chagasi
Where: South Asia, East
Leishmaniasis - Diagnosis ... Neutralization of complement ... Lymphohistiocytosis • Anemia ... culture, PCR, K39) Treatment ... #management #treatment
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
Celiac Disease - Diagnosis ... Algorithm Celiac ... Iron-deficiency anemia ... unresponsive to treatment ... Celiac #Disease #Diagnosis
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
approach to the diagnosis ... imprecise, and complemented ... and to adjust treatment ... #Diagnosis #Management ... Thrombocytopenia #Algorithm