19 results
diagnosis differential management rheumatology vasculitis hematology nephrology testing workup classification disease glomerular glomerulonephritis nephrotic urticarial aafp acyclovir agglutinin anemia calcium
Diagnosis and Management of Hypocomplementemic Urticarial Vasculitis (HUV) Diagnosis of HUV 1) Chronic urticaria 2) Leukocytoclastic vasculitis 3)
Management of Hypocomplementemic ... Urticarial Vasculitis (HUV ... Diagnosis of HUV ... vasculitis 3) Hypocomplementemia ... TerrierBen #Hypocomplementemic
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology of Hypocomplementemic ... Complex Formation - Complement ... TerrierBen #Hypocomplementemic ... Urticarial #Vasculitis #HUV
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... A - Atypical HUS ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... (Low levels mixed ... • HBV HCV •
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
anti-GBM) 10%: - Low ... Complement Levels ... Vasculitis - Normal Complement ... hypertension - MAHA: HUS ... , atypical HUS,
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low ... Complement: Post-strep ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Differential Diagnosis Algorithm ... perfringens - Complement-Mediated ... MAHA (TTP, DIC, HUS ... Differential #Diagnosis #Algorithm
Hypocalcemia Workup - Differential Diagnosis Algorithm • Low Magnesium, High Magnesium - Functional Hypoparathyroidism • High
Differential Diagnosis Algorithm ... • Low Magnesium ... High Phosphate, Low ... Infiltrative disorders, HIV ... Differential #Diagnosis #Algorithm
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
HTN • Check: HBV ... Elevated AST ALT • Hypocomplementemia ... Vasculitis) • Hypocomplementemic
Complement Deficiency Testing Algorithm • Normal CH50 and AH50 AND High suspicion for complement deficiency •
Complement Deficiency ... Testing Algorithm ... deficiency • Low ... Normal AH50 • Low ... Deficiency #Testing #Algorithm
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