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differential nephrology neurology hematology management pediatrics peds dermatology endocrinology obgyn workup acute ddxof cardiology obstetrics chronic em hepatology ophthalmology rheumatology
Diagnosis and Management of Hypocomplementemic Urticarial Vasculitis (HUV) Diagnosis of HUV 1) Chronic urticaria 2) Leukocytoclastic vasculitis 3)
Diagnosis and Management ... of Hypocomplementemic ... Vasculitis (HUV) Diagnosis ... vasculitis 3) Hypocomplementemia ... TerrierBen #Hypocomplementemic
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... CHAMPS #Mnemonic #diagnosis
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology of Hypocomplementemic ... Complex Formation - Complement ... TerrierBen #Hypocomplementemic
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... tract, and often causes ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement
Causes of Hemolytic Anemia - Differential Diagnosis Inherited • Membrane • Internal - Hemoglobin
Causes of Hemolytic ... - Differential Diagnosis ... Antibody/DAT+ - Complement ... #Differential #Diagnosis ... #Causes #hematology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Idiopathic • Normal Complement ... #differential #diagnosis ... #algorithm #rheumatology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... - Differential Diagnosis ... Algorithm Extravascular ... perfringens - Complement-Mediated ... #Algorithm #Causes
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
PET-CT Imaging (→ Diagnostic ... rheumatoid factor), ± hypocomplementemia ... glucocorticoids - reconsider diagnosis ... Related #Disease #diagnosis
Causes of Nausea and Vomiting - Differential Algorithm #Diagnosis #EM #IM #Causes #Nausea #Vomiting #Differential #NonGI
Causes of Nausea ... - Differential Algorithm ... #Diagnosis #EM ... #IM #Causes #Nausea ... Differential #NonGI #Algorithm
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
dysmorphic RBC, RBC casts ... staining (lg + complement ... MGPN • Complement ... of alternative complement ... MPGN #nephrology #diagnosis
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