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diagnosis rheumatology erythematosus lupus neurology spinalcord vasculitis agglutinin anemia c3 classification cord criteria disease disorders hematology hemolytic injury nerveroots slicc
Effect of Selected Diseases on Complement Levels - C3, C4 • SLE C3 ↓ C4 ↓↓
Selected Diseases on Complement ... Levels - C3, C4 ... • SLE C3 ↓ C4 ... #Levels #C3 #C4 ... #differential #
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... CRITERIA - ANA level ... anticoagulant - Low complement ... (C3, C4, or CH50 ... #Rheumatology #SLE
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... (Low levels mixed ... vasculitis, and SLE
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin ... hemolysis • C3↓ C4 ... younger pts) Differential ... temperatures by fixing complement ... Symptoms: High fevers
Spinal Cord Injury by Nerve Root Levels Spinal Root Sensory Motor Reflex C4 Acromioclavicular Joint Respiration None C5 Radial Antecubital Fossa Elbow Flexion Biceps Reflex C6 Dorsal Thumb Wrist Extension Brachioradialis Reflex C7 Dorsal
Spinal Cord Injury ... by Nerve Root Levels ... Motor Reflex C4 ... Abduction None T7-T12 See ... #differential #
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
- Differential ... Pain reported at level ... Behcet disease - SLE ... diagnosis #neurology #differential ... #algorithm
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... permanent alopecia Differential ... levels (C3 and ... C4) • ds-DNA: Kidney ... activity • C3 C4
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... diseases, such as SLE ... Vasculitis: • Fevers ... Elevated AST ALT • Hypocomplementemia ... Vasculitis) • Hypocomplementemic
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