13 results
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology ... normally inactivates GLP ... not definitively cause ... #Summary #DM2 #diabetes ... #endocrinology
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
Action for Common Diabetes ... Meglitinides • GLP ... Receptor Agonists • DPP4i ... #Medications #pharmacology ... pathophysiology #endocrinology
Oral Hypoglycemics in Diabetes Management
1  INSULIN SENSITIZER
 • TZD 
     -
Oral Hypoglycemics ... (Adlyxin) • DPP ... by inhibiting DPP ... #pharmacology # ... DM2 #DMII #Classification
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
a low risk of hypoglycemia ... very similar to DPP4s ... #Pharmacology #Dosing ... #Diabetes #DM2 ... #Endocrinology
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
Diabetes Medications ... Summary Table ... Sulfonylureas GLP ... events TZDs DPP ... comparison #management #endocrinology
Comparison of anti-diabetic or anti-hyperglycemic agents

There are numerous anti-hyperglycemic agents available to manage Type 2 diabetes.
Comparison of anti-diabetic ... and compares the hypoglycemia ... #pharmacology #pharmacotherapy ... #table #comparison ... #endocrinology
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Increase Incretins (GLP-I ... minimal chance of hypoglycemia ... Renal #Dosing #Pharmacology ... #Management #Diabetes ... #DM2 #Endocrinology
Effects on body weight of various classes of type-2 diabetes medications.
 - Metformin - Weight Loss
weight of various classes ... of type-2 diabetes ... Weight Loss ++ - GLP ... Weight Loss +++ - DPP ... weightgain #comparison #pharmacology
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
- Pharmacology ... Ozempic), or daily tablet ... not definitively cause ... #Summary #DM2 #diabetes ... #endocrinology
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Sulfonylurea, TZD, DPP ... -4 inhibitor, GLP ... #Medications #pharmacology ... #comparison #table ... #endocrinology