24 results
Diabetes – diabetic nephropathy
Majority of the literature in the area is applied to the diabetic nephropathy
- Chronic hyperglycemia ... be the primary cause ... hyperfiltration - Hyperglycemia ... - Cytokines #Pathophysiology
Hydroxyurea - Pathophysiology and Benefits in Sickle Cell Disease
 • Decreases number of pain crises (
Hydroxyurea - Pathophysiology ... number of pain crises ... Benefits #SickleCell #pathophysiology ... #pharmacology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... agent • Does not cause ... hypoglycemia ... e.g. diarrhea, nausea ... #Metformin #Pharmacology
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Diarrhea, Insomnia, Nausea ... gain Incr NE: Nausea ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... #Pharmacology #
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Drug-induced edema is caused ... Edema #Medication #Causes ... #Differential #Pharmacology ... #Pathophysiology
Drug-Induced Seizures - OTIS-CAMPBELL

O - Organophosphate, oral hypoglycemics, opioid
T - TCA, theophylline
I - Isoniazid, Insulin
S -
Organophosphate, oral hypoglycemics ... Seizures #Medication #Causes ... #Differential #Pharmacology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... ascites, jaundice, hypoglycemia ... diagnosis #management #pathophysiology
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Dizziness - Nausea ... Serotonin #Inhibitors #Pathophysiology ... #Pharmacology #
Intern Pocket Cards - Inpatient Anti-Emetics Guide
Serotonin antagonists:
 • Ondansetron (Zofran), Granisetron (Kytril, Sancuso) - Headache,
Zyprexa) - EPS, hyperglycemia ... adrenal suppression, hyperglycemia ... pocketcardset #nausea ... #medications #pharmacology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... Hyperkalemia, Hypoglycemia ... #21HydroxylaseDeficiency #21OHD #pathophysiology