68 results
diagnosis management differential hematology pharmacology syndrome diabetes oncology classification lupus neurology sle algorithm cardiology dermatology erythematosus hemophagocytic hlh lymphohistiocytosis nephrology
Metformin Pharmacology Summary Mechanisms of Action: • Suppresses gluconeogenesis by the liver • Increases insulin-mediated glucose utilization
Metformin Pharmacology Summary ... hypoglycemia ... Chronic kidney disease ... • Severe liver disease ... #endocrinology
Sulfonylureas - Pharmacology Summary Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
- Pharmacology Summary ... : Weight gain, Hypoglycemia ... #Pharmacology #Summary ... #DM2 #diabetes ... #endocrinology
Type 2 Diabetes - Screening, Diagnosis and Management Algorithm Lifestyle Modifications (Diet and Exercise) -> Start
-> Start Oral Hypoglycemic ... Second Oral Hypoglycemic ... relative with DM2 ... • Secondary Causes ... PCOS), Pancreatic Disease
GLP-1 Receptor Agonists - Pharmacology Summary Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
- Pharmacology Summary ... atherosclerotic heart disease ... not definitively cause ... #DM2 #diabetes ... #endocrinology
SGLT2 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
- Pharmacology Summary ... atherosclerotic heart disease ... #Pharmacology #Summary ... #DM2 #diabetes ... #endocrinology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Erythematosus - Summary ... with more severe disease ... Treatment: • ... Erythematosus #SLE #Summary ... #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
and Management Summary ... Positive in 60-80% of cases ... life-threatening • Treatment ... Evolution: Chronic disease ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... Adult-onset Still disease ... Drugs, Unknown cause ... Treatment: • ... #summary #rheumatology
DPP-4 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology Summary ... not definitively cause ... #Pharmacology #Summary ... #DM2 #diabetes ... #endocrinology
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... by case) • Surgery ... #Syndrome #Treatment ... #pharmacology #rheumatology
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