11 results
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
- Pharmacology Summary ... : Weight gain, Hypoglycemia ... #Pharmacology #Summary ... #DM2 #diabetes ... #endocrinology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology Summary ... Does not cause hypoglycemia ... #Pharmacology #Summary ... #DM2 #diabetes ... #endocrinology
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
Diabetes Medications ... Summary Table ... EricsMedicalLectures/featured #diabetes ... comparison #management #endocrinology ... #dm2
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology of Diabetic ... deficit: - Type I DM ... food binges, etc Hyperglycemia ... pathophysiology #comparison #endocrinology ... #diabetes #diabetic
Summary and links to five landmark trials of intensive control vs standard therapy in DM2:

 UKPDS
Summary and links ... standard therapy in DM2 ... VisualAbstract #Endocrinology ... #PrimaryCare #Diabetes ... #DM2 #Type2 #Landmark
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
- Pharmacology Summary ... • Euglycemic diabetic ... #Pharmacology #Summary ... #DM2 #diabetes ... #endocrinology
Assessment of diabetic control:
 - Any episodes of hypoglycaemia, diabetic ketoacidosis, hospital admission? 
 - Is
Assessment of diabetic ... Any episodes of hypoglycaemia ... still awareness of hypoglycaemia ... #primarycare #DM1 ... #Peds #Pediatrics
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology Summary ... #Pharmacology #Summary ... #DM2 #diabetes ... #endocrinology
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
to treat Type 2 Diabetes ... a low risk of hypoglycemia ... Pharmacology #Dosing #Diabetes ... #DM2 #Endocrinology
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
- Pharmacology Summary ... #Pharmacology #Summary ... #DM2 #diabetes ... #endocrinology