19 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... patients sensitive to high ... of aspiration #Potassium ... #medications #pharmacology ... #table #comparison
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Gitelman's syndrome #Hypokalemia ... #Differential # ... Diagnosis #Algorithm #nephrology ... #causes #low #potassium
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Syndrome • HTN, High ... Diagnosis #Algorithm #causes ... #potassium #low ... #nephrology
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... intracellular calcium causes ... high potassium levels ... (or low potassium ... Pathophysiology #cardiology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
diuresis can be high ... Present (Uosm ≥100): Hypovolemia ... #differential # ... diagnosis #table ... #sodium #nephrology
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
Causes of Hypernatremia ... water loss, Serum Sodium ... >145 mmol/L High ... mannitol, glucosuria Low ... #Nephrology #Differential
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
urinary losses: • High ... consumption • Low ... diagnosis #Algorithm #differential ... #potassium #nephrology ... #low
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... lysis syndrome - Rhabdomyolysis ... diagnosis #causes ... #potassium #high ... #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Differential Diagnosis ... Management Summary Causes ... Hyperuricemia • Hyponatremia ... Monitor potassium ... #treatment #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... lysis syndrome - Rhabdomyolysis ... diagnosis #causes ... #potassium #high ... #nephrology