10 results
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... Hypercalcemia ... #Causes #differential ... #diagnosis #calcium ... #high #endocrinology
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Hypercalcemia - ... Differential Diagnosis ... Hypocalciuric Hypercalcemia ... Thiazides/Lithium #Hypercalcemia ... #causes #endocrinology
Causes of Hypercalcemia
Parathyroid gland structure-related
 • Primary hyperparathyroidism
 • Parathyroid adenoma
 • Parathyroid hyperplasia
 • Parathyroid
Causes of Hypercalcemia ... hypocalciuric hypercalcemia ... Milk-alkali syndrome #Hypercalcemia ... #Causes #endocrinology ... #diagnosis #differential
Hypercalcemia Evaluation
1) Clinical clues
 - Is the patient symptomatic?
 - Family history?
 - Have you done
Hypercalcemia Evaluation ... BrighamChiefs #Hypercalcemia ... #workup #differential ... #diagnosis #endocrinology ... #calcium #elevated
Causes of Hypocalcemia by Clinical Cause

Acute illness: pancreatitis, tumor lysis, severe illness - Secondary hyperparathyroidism from
Causes of Hypocalcemia ... Family history of hypocalcemia ... #Hypocalcemia ... #Causes #Differential ... #Diagnosis #Endocrinology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... pain • loss of secondary ... ALP -> PPi and Calcium ... Hyperlipidemia - Hypercalcemia ... #Hyophosphatasia
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Diagnosis Algorithm ... Endocrine • Hyperparathyroidism ... Sarcoidosis • Hypercalcemia ... #endocrinology ... #causes
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Endocrine: Hypo/Hyperthyroidism ... Hyperphosphatemia • Hypocalcemia ... /Late - Hypercalcemia ... Hyperuricemia • Hyponatremia ... potassium and calcium
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Causes of Secondary ... Diagnosis Approach ... (when evaluation ... Vasculitis • Endocrinologic ... , Hypercalcemia,
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
thyroiditis Secondary ... ↑ T3 - Mild hypercalcemia ... #causes #diagnosis ... #differential # ... endocrinology #signs