12 results
Hypocalcemia Laboratory Evaluation

Serum levels of PTH, phosphorus, 25-hydroxyvitamin D, and 1,25-dihydroxyvitamin D can help differentiate between
dihydroxyvitamin D can help differentiate ... : - Hypoparathyroidism ... - Calcium-sensing ... #Diagnosis #Endocrinology ... #Differential
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
resorption: • Primary hyperparathyroidism ... histoplasmosis) • Milk (calcium ... #Causes #differential ... #diagnosis #calcium ... #high #endocrinology
Hypercalcemia - Differential Diagnosis Algorithm
Primary Hyperparathyroidism
 • Adenoma
 • Hyperplasia
 • MEN 1 and 2A
Tertiary Hyperparathyroidism
Differential Diagnosis ... Autosomal Dominant Calcium ... Other • Excess Calcium ... #Differential # ... Diagnosis #Algorithm #Endocrinology
MOVE STUPID - Mnemonic for Altered Mental Status (Delirium)
 - Metabolic (hypercalcemia, hyponatremia)
 - Oxygen (hypoxia)
Mental Status (Delirium ... - Metabolic (hypercalcemia ... , hyponatremia) ... hypoglycemia) - Seizures ... encephalopathy #differential
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
Tertiary Lab Comparison ... : ↑→PTH, ↑Calcium ... : ↑PTH, ↓→Calcium ... Disorientation, Delirium ... #diagnosis #endocrinology
Hypocalcemia - Differential Diagnosis Algorithm - Low and High Phosphate
LOW PHOSPHATE
 - Low/NormaI PTH
Hypocalcemia - Differential ... ) • Calcium ... Poisoning #Hypocalcemia ... #Differential # ... Algorithm #Phosphate #endocrinology
Hypomagnesemia (Serum level < 1.7 mg/dL)
Neuromuscular manifestations 
 • Tremor, tetany, seizures 
 • Weakness
Tremor, tetany, seizures ... • Apathy • Delirium ... Abnormalities of calcium ... metabolism • Hypocalcemia ... • Hypoparathyroidism
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Differential Diagnosis ... normal): • Primary Hyperparathyroidism ... Bony Mets - Calcium ... #Differential # ... Algorithm #causes #endocrinology
Causes of Hypercalcemia
Parathyroid gland structure-related
 • Primary hyperparathyroidism
 • Parathyroid adenoma
 • Parathyroid hyperplasia
 • Parathyroid
structure-related • Primary hyperparathyroidism ... Lithium use • Calcium-sensing ... disease • Tertiary hyperparathyroidism ... #Causes #endocrinology ... #diagnosis #differential
Causes of Hypocalcemia by Clinical Cause

Acute illness: pancreatitis, tumor lysis, severe illness - Secondary hyperparathyroidism from
illness - Secondary hyperparathyroidism ... low circulating calcium ... Genetic defects in calcium-sensing ... #Causes #Differential ... #Diagnosis #Endocrinology