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management syndrome oncology sle erythematosus systemic vasculitis algorithm arthritis chronic classification cll cryoglobulinemia dermatology differential druginduced leukemia lymphocytic neurology activation
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... • Immunologic Workup ... life-threatening • Treatment ... Evolution: Chronic disease ... #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... Treatment: • ... #Systemic #Lupus ... #diagnosis #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Cerebrovascular Disease ... autoantibodies that will cause ... permeability Diagnosis ... CNS #neurology #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Discontinuation of causal ... Evolution: Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Drugs, Unknown cause ... Treatment: • ... #summary #rheumatology
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group < 5%
, causes and management ... cryoglobulinemia vasculitis Clinical ... neuropathy Treatment ... with refractory disease ... Cryoglobulinemia #Vasculitis #Rheumatology
Kawasaki Disease (KD) - Diagnosis and Management Summary Kawasaki Disease (KD) is the most common vasculitis of
Kawasaki Disease ... and Management Summary ... , Cough • +/-Nausea ... KD #vasculitis #rheumatology ... #management #treatment
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... Clinical history ... IgG4 #Related #Disease ... #phenotypes #workup ... #treatment #rheumatology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Better call hematology ... always a good idea ... As with many disease ... #Algorithm #workup ... #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Summary ... : • + Clinical ... cryoglobulins • Negative causes ... #rheumatology # ... hematology
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