18 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... → Refer to hematology ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Diagnosis #Algorithm #hematology
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
bronchiectasis, sinusitis ... signs of chronic sinusitis ... hypertension • ... mycobacteria Treatment ... #differential #
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... Myelofibrosis Infectious ... effect following treatment ... Thrombocytosis #Differential ... Algorithm #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... vasculitis, malignant hypertension ... inclusions - If infection ... Hemolytic #Anemia #Differential ... Algorithm #workup #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
: 33% • Treatment ... , and CXR with pulmonary ... ) • Fever and hypotension ... : No • Treatment ... Transfusion #Reactions #hematology
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm
Structural Defect - Asplenia/HypospIenism
 • Bacteremia/Septic
Immunocompromised Host - Differential ... • Perirectal Infection ... • Recurrent Sinusitis ... ImmuneCompromised #Differential ... Algorithm #Causes #Hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
drug reaction, infection ... Strongyloides infection ... glucocorticoid treatment ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
host): • Chronic pulmonary ... symptoms • Rheumatologic ... Histoplasmosis Treatment ... : • Pulmonary ( ... 60%) • Sinusitis
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Neutrophil (Normal) Differential ... overlook severe infections ... bacteremia and hypotension ... #Bandemia #differential ... neutrophil #WBC #CBC #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Diaqnoses: • Infectious ... hepatitis • Pulmonary ... diagnosis #management #treatment ... #rheumatology