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differential sle dermatology management signs vasculitis erythematosus arteritis autoimmune comparison cryoglobulinemia cryoglobulins disorders druginduced gca giantcell lymphomas lymphoproliferative manifestations monkeypox
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions - Inflammatory
Vesiculobullous Skin ... Rash - Differential ... Diagnosis Algorithm ... lupus erythematous ... #Algorithm #causes
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... inflammation on skin ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... Disease Classification ... : • Symptoms limited ... #Diagnosis #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... Discontinuation of causal ... months to years) Systemic ... comparison #table #rheumatology ... #diagnosis #management
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... symptoms by days ... Causes: - Idiopathic ... ’s syndrome - Lupus
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Algorithm Hodgkin ... pattern of spread, B symptoms ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #Hematology #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... mucositis - Rash ... Symptoms (Sx) in ... #rheumatology # ... classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... lupus erythematosus ... #types #classification ... #rheumatology #
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
and ophthalmic complications ... required due to skip ... them, but urgent rheumatology ... absence of visual symptoms ... Temporal #Signs #Symptoms
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