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differential management causes oncology algorithm erythematosus lupus lymphoma mcv sle systemic workup abnormal activation atlas autoantibodies beaus chronic clinical cll
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
e.g., HIV), EBV infection ... the spleen or liver ... translocation • Types: Classification ... • Other hematologic ... #differential #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
- Differential Diagnosis ... Renal Disease, Liver ... Inflammation, Chronic Infection ... #MCV #Classification ... Algorithm #Causes #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Weight loss • Anemia ... number of sites of disease ... #classification ... #hematology #oncology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Extrinsic Causes: • Liver ... disease • Hypersplenism ... drug induced • Infections ... #causes #classification ... #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential Diagnosis ... Macroangiopathic, Infections ... Non-megaloblastic: Liver ... disease, Alcoholism ... #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... - Hemolytic anemia ... SLE) - Viral infections ... deficiency • Liver ... #hematology #rheumatology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... Defects, Drugs, Liver ... Internal (RBC) - Infections ... Defects: Sickle cell anemia ... #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
late adulthood • Diagnosis ... • Liver diseases ... autoimmune hemolytic anemia ... conditions Diagnosis ... hypogammaglobulinemia #immunology #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... procedures - Infection ... changes), high MCV anemia ... disease), HBsAg ... Causes #Workup #hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Hemolytic anemia ... Other auto-immune, Infectious ... diseases, Hematological ... autoantibodies #signs ... #differential #rheumatology
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