15 results
LVOTO due to SAM on POCUS Echocardiogram

Septic patient after IV fluids and initiation of Levophed. Worsening
Echocardiogram ... Diagnosis? ... Management? ... #ultrasound #Cardiology ... #PLAX #clinical
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Symptomatic anemia Diagnosis ... megaloblastic anemia Treatment ... neutropenic fever ... #management #treatment ... #hematology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Life-threatening ... synovitis (40%) Treatment ... Disease #AOSD #rheumatology ... #diagnosis #management ... #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... , ↓ Fibrinogen level ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Treatment - Mild ... : NSAIDS Treatment ... • If uncontrolled ... #rheumatology # ... management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
following: • Fever ... • Bicytopenia Treatment ... If no response HLH ... #management #treatment ... #hematology
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
thoracotomy is a better treatment ... tamponade recurs. ❿ Plan ... definitive management ... specialist referral. ⓫ Plan ... #Management #Workup
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... high risk if WBC ... Subacute-Acute: • Common: fever ... Renal Failure Treatment ... #management #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... organ damage • Treatment ... : - If febrile ... Syndrome #TLS #diagnosis ... #management #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
DIC • Severe Liver ... dL) - Heparin if ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology