32 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... Management Summary ... nephritis, NPSLE - If ... Erythematosus #Diagnosis ... #rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... CRITERIA - ANA level ... Anti-dsDNA antibody level ... reference range if ... #Rheumatology #
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
erythematosus [SLE ... ALT ↑ bilirubin level ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
ANA) [especially if ... 9) Unexplained fever ... including in children (pediatric ... SLE) 10) When ... erythematosus #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... , ↓ Fibrinogen level ... Autoimmune diseases: SLE ... #management #treatment ... #summary #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... be available (i.e ... (to support a diagnosis ... laboratory #workup #diagnosis ... #testing #Rheumatology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Symptomatic anemia Diagnosis ... neutropenic fever ... Aplastic #Anemia #diagnosis ... #management #treatment ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... test, ANA (e.g., SLE ... a primary hematologic ... #Differential #Diagnosis ... Causes #Workup #hematology
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Disease (KD) - Diagnosis ... and Management ... Criteria - Fever ... KD #vasculitis #rheumatology ... #pediatrics #diagnossi
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
nephritis, NPSLE - If ... Prognosis: Minor to life-threatening ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management