15 results
Intravenous Lipid Emulsion (ILE) Therapy

ILE is a treatment for severe toxicity from local anesthetics. In addition,
) Therapy ILE ... treatment for severe toxicity ... toxicity from: ... #Therapy #Toxicology ... #Management #Pharmacology
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Salicylate Toxicity ... Consider if: ... , Diaphoresis, Pulmonary ... Toxic Salicylate Level ... #Toxicology #diagnosis
Amiodarone Toxicity and Monitoring

Tremor Ataxia 
Ocular neuritis 
Corneal Microdeposits 
Bradycardia 
Pulmonary fibrosis 
Hepatotoxicity 
Blue-gray skin
Amiodarone Toxicity ... Bradycardia Pulmonary ... Distribution - Half life ... Adverse #Diagnosis #Management ... #Pharmacology
Therapeutic Drug Level Monitoring 
Carbamazepine - Sample immediately before next dose (trough) 
Clozapine - Sample immediately
Therapeutic Drug Level ... or at anytime if ... toxicity suspected ... Therapeutic #Ranges #Toxicology ... #Pharmacology #
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... metabolized in the liver ... #Clozapine #Toxicology ... #Toxicity #Diagnosis ... #Pharmacology
Salicylate Poisoning - Toxicology

Acute toxicity = vomiting, tachypnea, tinnitus, diaphoresis, and lethargy. This may progress to
Salicylate Poisoning - Toxicology ... hyperthermia, coma, and pulmonary ... Cerebral and pulmonary ... #Toxicology #Pharmacology ... #Diagnosis #Management
Naloxone - Toxicology

Adult starting dose:
 - 0.4 mg IV/IM/IO/SQ for non-opioid dependent patients
 - 0.04 mg
Naloxone - Toxicology ... opioid-dependent patients Pediatric ... If an infusion is ... Naloxone #Narcan #Toxicology ... #Management #Pharmacology
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
Amiodarone half life ... Fever 4. ... pneumonia - Pulmonary ... #Pulmonary #diagnosis ... #management #Toxicology
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
tool to assess level ... glycol (solvent) toxicity ... No pharmacologic ... (Haldol) - No pharmacologic ... CriticalCare #diagnosis #management
Digoxin Pharmacology and Monitoring

 • Digoxin’s half-life is 30-45 hours in healthy adults
 • When monitoring
Digoxin Pharmacology ... Digoxin’s half-life ... Kat_Watson #Digoxin #Pharmacology ... #Monitoring #toxicology ... #management #toxicity