19 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Diagnosis and Management ... • Immunologic Workup ... Evolution: Chronic disease ... #Summary #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Systemic lupus ... manifestations: from easy bruising ... ALT ↑ bilirubin level ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
and Arthritis in Pediatrics ... Patient - Differential ... not be seen try focus ... Suggestive of: Rheum Fever ... gabrieltalledop #dermatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
Bleeding and Bruising ... of Hemostasis - Differential ... inhibitor and lupus ... #Bleeding #Bruising ... #Diagnosis #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... disease, decrease ... disease), HBsAg ... #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... RBC inclusions - If ... bartonella (oroya fever ... Diagnosis #Algorithm #workup ... #hematology #testing
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... • Immunologic Workup ... Usual therapeutic management ... Evolution: Chronic disease ... #diagnosis #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... permanent alopecia Differential ... (i.e. fibromyalgia ... Malignancy (e.g. hematologic ... vein thrombosis Hematologic
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... dependent injury (ie ... disease 6-9 mo ... Idiosyncratic #differential ... gastroenterology #hepatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
the face (many differential ... ANA) [especially if ... 9) Unexplained fever ... including in children (pediatric ... erythematosus #rheumatology