61 results
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Hypothyroid • Liver ... Disease • Alcohol ... diagnosis #algorithm #hematology ... #workup
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... Autoimmune Mediated ... Autoimmune condition ... Metastatic Disease ... Diagnosis #Algorithm #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
RBC inclusions - If ... bartonella (oroya fever ... elliptocytosis, autoimmune ... Diagnosis #Algorithm #workup ... #hematology #testing
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... Autoimmune Mediated ... Autoimmune condition ... Metastatic Disease ... Diagnosis #Algorithm #Hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Folate deficiency, Liver ... spherocytosis, Autoimmune ... stomatocytosis, Liver ... Agglutinate: Cold autoimmune ... differential #diagnosis #hematology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
) • Advanced Liver ... Disease - Alcohol ... Viral hepatitis, Autoimmune ... - Malignancy, Autoimmune ... comparison #diagnosis #hematology
Autoimmune Hemolytic Anemia (AIHA) Treatment
Warm AIHA:
1) Steroids - 1-2 mg/kg prednisone daily
   • Until
Autoimmune Hemolytic ... severe disease ... BrighamMedRes #AIHA #Autoimmune ... AIHA #Treatment #management ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
EBV infection, Autoimmune ... but might occur if ... Pylori) - Autoimmune ... Lymphomas • Other hematologic ... #differential #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Extrinsic: Autoimmune ... Non-megaloblastic: Liver ... disease, Alcoholism ... Differential #Diagnosis #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Membrane): - Autoimmune ... Defects, Drugs, Liver ... Disease, PNH ... Electrolytes: Wilson's disease ... Differential #Diagnosis #hematology