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diagnosis clinical differential rheumatology physicalexam management lupus causes erythematosus neurology algorithm pocus pulmonary systemic cardiology ultrasound ophthalmology radiology syndrome msk
Lupus Nephritis Primer Class I - Minimal Mesangial Class II - Mesangial Proliferative Class Ill - Focal Proliferative Class IV
Proliferative Class Ill ... Lupus #Nephritis #SLE ... #Classification
Renal Involvement in Systemic Lupus Erythematosus Dr. Laurent ARNAUD @Lupusreference #Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Renal #diseases #SLE ... nephrology #nephritis #classification
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
in 10 to 40% of SLE ... severity (ISN/RPS classification ... by 12 months Classification ... : active Ill ... chronic lesions Ill
Clinical Manifestations of Systemic Lupus Erythematosus (SLE) #Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Erythematosus (SLE ... Erythematosus #SLE
Systemic Lupus Erythematosus (SLE): Pathogenesis • Genetic factors (Mutations in HLA- DR2/HLA-DR3 genes, complement genes, cytokine
Erythematosus (SLE ... system defects (i.e ... Interferon-a, IL ... -6, IL-10 #Systemic ... Erythematosus #SLE
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Spondyloarthropathies, SLE ... retinal exudates) - SLE ... nodules - RA, SLE ... disease - RA - SLE ... • Seizures - SLE
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Highly specific for SLE ... Association with both SLE ... Anti-Ribo-P 5-15% If SLE ... higly specific for SLE ... patients with typical SLE
Classification of COVID-19 Disease States and Potential Therapeutic Targets Viral Response Phase -> Host Inflammatory Response Phase Stage
Classification of ... Phase) Stage Ill ... immunoglobulin, IL ... -6 inhibitors, IL ... #Progression #Classification
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
pattern: - SLE ... pattern: - SjS, SLE ... Speckled: - SLE ... conditions, SjS, SLE ... Golgi/polar: - SLE
Monoarthritis - Differential Diagnosis Infection (Acute): - S. aureus (most common) - S. pneumonia - Salmonella (in
Gout- usually LE ... arthritis - SLE
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