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differential nephrology treatment acute algorithm hematuria urology blood kidney rhabdomyolysis atlas glomerulonephritis hyperkalemia k key kidneyinjury macroscopic membranoproliferative microscopy mpgn
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
• Evidence of glomerular ... proteinuria, RBC casts ... for renal biopsy ... if cause not identified ... by UW IM Residency
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
microscopy • Red cell casts ... • White cell casts ... • Hyaline casts ... disease • Granular casts ... #nephrology #casts
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... and Differential Diagnosis ... #AKI #Workup #Algorithm ... #nephrology #causes
Acute Kidney Injury - Differential Diagnosis Framework PRERENAL: - Intrarenal vasoconstriction-hemodynamically mediated - Systemic vasodilation - Volume
INTRINSIC: - Glomerular ... white blood cell casts ... tubular cell casts ... or pigmented casts ... #AKI #Differential
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
- Differential Diagnosis ... Immune mediated injury ... hematuria: - RBC casts ... #causes #urology ... #nephrology #renal
Simplified Approach to Acute Kidney Injury (AKI) 1) IS THIS AN EMERGENCY? Is there a dialysis indication
to Acute Kidney Injury ... cases are caused ... IMPROVEMENT If the urine ... for WBCs, RBCs, casts ... #diagnosis #nephrology
Algorithm and Differential Diagnosis of Macroscopic Hematuria Important Historical Elements: - Painless: suggests malignancy - Painful: suggests calculi/infection - Urinalysis:
and Differential Diagnosis ... RBC’s, RBC/WBC casts ... suggest intrinsic renal ... #EM #IM #Urology ... Differential #Algorithm #Ddxof
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
GN • Active Urine ... dysmorphic RBC, RBC casts ... formation along glomerular ... immune deposits on EM ... #diagnosis #renal
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
and Management ... Dermatomyositis) AKI ... Cast formation: ... hour with goal urine ... #causes #treatment
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... Framework and Management ... Summary Causes ... Cast formation: ... #Management #causes
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