9 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Positive in 60-80% of cases ... life-threatening • Treatment ... #Summary #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... (SLE) Clinical ... autoantibodies that will cause ... cerebritis #diagnosis #management ... #treatment
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Discontinuation of causal ... Systemic Lupus Erythematosus ... druginduced #lupus #sle #comparison ... #table #rheumatology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... without other cause ... , and CXR with pulmonary ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
lung disease Caused ... shunt (Type 2) Clinical ... cirrhosis • Intra-pulmonary ... ) on room air Treatment ... #treatment #hepatology
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
150 published cases ... Relapsing-remitting course +++ Clinical ... filling +++ (risk of pulmonary ... syndrome #diagnosis #management ... #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... , INC risk PE, Pulmonary ... Adenocarcinoma Treatment ... #Diagnosis #Management
Legionnaires' Disease
Clinical features:
 • Gl- nausea, vomiting, diarrhea
 • Hyponatremia
 • Elevated transaminases
 • CRP >100
Legionnaires' Disease Clinical ... respond to B-Lactams Treatment ... Extra-pulmonary: ... Hospital of Baltimore IM ... Disease #diagnosis #management
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
with edema • Erythematous ... auricular papules Clinical ... Muscle atrophy may cause ... positive patients Treatment ... Dermatomyositis #diagnosis #management