16 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... Differential Diagnosis: Infection ... #diagnosis #management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
marrow) -dys- (abnormal ... old, ~10,000 new cases ... risk-stratification • Risks: infection ... only curative treatment ... #treatment #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Diaqnoses: • Infectious ... CK, normal biopsy ... hepatitis • Pulmonary ... Disease #diagnosis #management ... #treatment #rheumatology
ED Treatment of 
Abnormal Uterine Bleeding 

Hemodynamically unstable 
Resuscitation 
 • ABCs! 
 • Fluids +
ED Treatment of ... pregnancy related cause ... increased risk of infection ... breast cancer IM ... Uterine #Bleeding #Management
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
host): • Chronic pulmonary ... symptoms • Rheumatologic ... level • A low or normal ... : • Pulmonary ( ... Fungal #Diagnosis #Management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... petechiae) • Frequent infections ... • Parvovirus infection ... Syndromes #diagnosis #hematology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Incidence: 1 to 2 cases ... to a preceding infection ... and cauda equina TREATMENT ... Hospital of Baltimore IM ... Syndrome #diagnosis #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Neutropenia - recurrent infections ... and petechiae Causes ... Idiopathic • Infections ... aplastic anemia Treatment ... #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Lymphadenitis, pulmonary ... lymphadenitis, pulmonary ... , hypoxia, and pulmonary ... leukoencephalopathy (PML ... Differential #Diagnosis #Management
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
150 published cases ... filling +++ (risk of pulmonary ... of infections) ... syndrome #diagnosis #management ... #rheumatology