3337 results
Thrombocytopenia 
Work up, differential diagnosis and management.

Satyendra Dhar MD, @DharSaty

#thrombocytopenia #platelets #ITP #DIC
Thrombocytopenia Work up, differential ... thrombocytopenia #platelets #ITP
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Thrombocytopenia - Differential ... Autoimmune • ITP ... HELLP Syndrome • TTP ... Thrombocytopenia #Differential
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Thrombocytopenia - Differential ... Microangiopathy: DIC, TTP ... Antibody-mediated: ITP ... Thrombocytopenia #Differential
Causes of Purpura - Differential Diagnosis
Non-PalpabIe → Palpable
 • Thrombocytopenia (HIT, ITP/HUS), Coagulation defects (DIC, warfarin
Causes of Purpura - Differential ... Thrombocytopenia (HIT, ITP ... palpable #Causes #Differential
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... following treatment of ITP ... Thrombocytosis #Differential
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... fulminans - DIC - TTP ... Non-Palpable Rash: - ITP ... APLS - HIT - ITP ... Petechiae #Rash #Differential
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm
Blood Loss: >500mL post vaginal delivery OR >1000 mL
Post-Partum Hemorrhage - Differential ... thrombocytopenic purpura (ITP ... thrombocytopenic purpura (TTP ... Hemorrhage #PPH #Differential
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
thrombocytopenia (ITP ... key #diagnosis #differential
PLATELETS Mnemonic for Causes of Thrombocytopenia

P - Platelet Disorders (DIC, ITP, TTP)
L - Leukemia, Lymphoma
A -
Disorders (DIC, ITP ... , TTP) L - Leukemia ... Thrombocytopenia #Differential
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... However, it may ... Refractory ITP, ... Platelet #Disorders #Differential