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Management of Immune Thrombocytopenia (ITP) . #Idiopathic #Thrombocytopenic #Purpura #Immune #Thrombocytopenia #ITP #Management #Hematology
Management of Immune ... Thrombocytopenic #Purpura #Immune ... ITP #Management #Hematology
Thrombocytopenia - Differential Diagnosis Algorithm Decreased production: • Bone marrow suppression • Bone marrow failure • Bone
disorders • Immune ... Diagnosis #Algorithm #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
hemolysis - Immune-Mediated ... • Drug-induced immune-complex ... Algorithm #Causes #Hematology
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
peripheral smear Immune-mediated ... Diagnosis #Algorithm #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Acquired • Immune ... • Non-lmmune ... Algorithm #Causes #Hematology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
P - Post/pauci immune ... #differential #hematology
Approach to Paraproteinemia An abnormal increase in monoclonal immunoglobulin fragments or intact immune globulins produced usually by
fragments or intact immune ... Paraproteinemia #diagnosis #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Syndrome - Non-immune ... Differential #Diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Hemolysis: • Immune-mediated ... differential #diagnosis #hematology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
primary or secondary immune ... Common variable immune ... ICL #diagnosis #hematology
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