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diagnosis hematology differential management treatment vasculitis algorithm causes cdc classification oncology parasite pathophysiology hemolysis amebiasis anemia blood dermatology erythematosus extravascular
The Spectrum of Tuberculosis As shown in the graphic from our Primer, exposure to M. tuberculosis can
because of innate immune ... eliminated the infection ... via innate immune ... with acquired immune ... ‏ #Diagnosis #InfectiousDiseases
Thrombocytopenia - Differential Diagnosis Algorithm Decreased production: • Bone marrow suppression • Bone marrow failure • Bone
infiltration • Infection ... disorders • Immune ... Diagnosis #Algorithm #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... that disrupts immune ... Still disease, Infection ... Others: Cellular immune ... treatment #summary #rheumatology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
hemolysis - Immune-Mediated ... circulation - Infections ... • Drug-induced immune-complex ... Algorithm #Causes #Hematology
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
Most invasive infections ... impaired cellular immune ... Rhinosinusitis, CNS infection ... , Disseminated infection ... treatment #fungal #infectiousdiseases
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
peripheral smear Immune-mediated ... Hypersplenism, Infection ... Diagnosis #Algorithm #hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
can activate the immune ... the deposit of immune ... Immune-Mediated ... : HCV infection, ... classification #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Hemolysis: • Immune-mediated ... Mycoplasma pneumoniae infection ... spherocytosis) • Infections ... differential #diagnosis #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
• Others Non-lmmune ... Vasculitis • Infection ... Algorithm #Causes #Hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Syndrome - Non-immune ... Internal (RBC) - Infections ... Differential #Diagnosis #hematology
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