1209 results
Immune Checkpoint Inhibitor Toxicity

Main Toxicities: Colitis,  
Pneumonitis, Skin adverse events, Endocrine dysfunction, 
Hepatitis,  
Myocarditis,
Immune Checkpoint ... Incidence, Symptoms ... Treatment #Immune ... #Pharmacology #Oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
mutations) • Immune ... HCV - HIV • Immune ... • Improve the symptoms ... Aplastic #Anemia #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
rendering the immune ... with no early symptoms ... diagnosis #workup #oncology
Management of Immune Checkpoint Inhibitor (ICI) Induced Cardiotoxicity
Problem - Immune checkpoint inhibitors (ICIs) are associated with
Management of Immune ... Cardiotoxicity Problem - Immune ... resolution of symptoms ... tests with mild symptoms ... Cardiotoxicity #cardiology #oncology
Signs and Symptoms of Acute Leukemia

#Leukemia #Signs #Symptoms #Acute #Diagnosis #Oncology
Signs and Symptoms ... Leukemia #Signs #Symptoms ... Acute #Diagnosis #Oncology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Erythema nodosum • Immune ... ingestion • B symptoms ... classification #hematology #oncology
Melanoma Pathogenesis

Environmental exposure (UV light) + genetic susceptibility (CDKN2A, CDK4, MC1R, BRAF, p16/ARF genes) → accumulation
invasion, evasion of immune ... Pathophysiology #Oncology
Check point inhibitors and Side Effects - Immune-related adverse events (IRAEs)

What are the side effects?
 -
Side Effects - Immune-related ... - Immune-related ... - Most immune-related ... AdverseEffects #Oncology
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
Bowman's space) Immune-Complex ... • Presence of immune ... deposits Pauci-lmmune ... • Minimal immune
Eosinophilic Esophagitis (EoE) - Spectrum of Response
Non-response:
 • Histology: Persistent eosinophilia, ≥ 15 eos/hpf
 • Symptoms:
15 eos/hpf • Symptoms ... : Persistent symptoms ... decrease in a symptom ... : Decreased symptoms ... : Symptom resolution