22 results
diagnosis management signs hematology neurology syndrome treatment vasculitis algorithm als amyotrophic anemia aplastic apml barre benign bph carcinogenesis cardiology cardiotoxicity
Melanoma Pathogenesis Environmental exposure (UV light) + genetic susceptibility (CDKN2A, CDK4, MC1R, BRAF, p16/ARF genes) → accumulation
invasion, evasion of immune ... #Pathophysiology ... #Oncology #Melanoma
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Manifestations • Immune ... Complications #pathophysiology ... #signs #symptoms
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare but potentially serious adverse reaction that has been
Vaccine-induced immune ... Symptoms of VITT ... and neurological symptoms ... Vaccine #Induced #immune ... thrombocytopenia #COVID #pathophysiology
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Nodules • Auto-immune ... Alopecia • Auto-immune ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
a dysregulated immune ... PolyarteritisNodosa #Pathophysiology ... Diagnosis #Signs #Symptoms
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
cell-mediated immune ... - Formation of immune ... HenochScholeinPurpura #Pathophysiology ... Diagnosis #Signs #Symptoms
Immune Checkpoint Inhibitor Toxicity Main Toxicities: Colitis, Pneumonitis, Skin adverse events, Endocrine dysfunction, Hepatitis, Myocarditis,
Immune Checkpoint ... Incidence, Symptoms ... Treatment #Immune ... #Pharmacology #Oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
mutations) • Immune ... HCV - HIV • Immune ... • Improve the symptoms ... Aplastic #Anemia #oncology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Pathogenesis: • Immune ... • Immune response ... than one after symptom ... the underlying pathophysiology ... + Intravenous Immune
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... management #hematology #oncology
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