60 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Hypereosinophilic Syndrome • Clinically ... suspect underlying hematologic ... disordersDiagnosis ... Syndrome #HES #Hematology ... #eosinophils #diagnosis
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
Non-hemolytic Disorders ... as jaundice on clinical ... • Disorder is ... Congenital #bilirubin #hepatology ... #diagnosis #gastroenterology
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Petechiae/Purpura - Diagnostic ... Pathophysiology: ... vasculitis) or disorders ... pulmonary #Diagnosis ... #Dermatology #Rash
Lewy Body Dementia: Pathogenesis and Clinical Findings
Lewy Body Dementia is a sub-category of major or mild
Pathogenesis and Clinical ... neurocognitive disorders ... Clinical manifestations ... sleep behavior disorder ... LewyBody #Dementia #pathophysiology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Headache, Movement disorders ... , Seizure disorders ... Disease, PRES Pathophysiology ... permeability Diagnosis
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... - Differential Diagnosis ... Lymphoproliferative #Disorders ... Classification #pathophysiology ... #Hematology #Diagnosis
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease Pathophsiology ... Lysosomal storage disorder ... in macrophages Diagnosis ... in GBA1 gene Clinical ... Gauchers #Disease #Diagnosis
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
inherited bleeding disorder ... Clinical • ... VonWillebrand #Disease #Diagnosis ... #Hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... infection, autoimmune disorder ... Viral Infection Clinical ... Monoclonal IgM Includes Disorders ... hemolytic #anemia #hematology
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... multifactorial mechanisms Hematologic ... disorders, lenectomy ... Systemic disorders ... Classification #Diagnosis