14 results
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
Algorithm for workup ... of thrombocytopenia ... hemolytic uremic syndrome ... , Hematology 2012 ... , p 193 #Diagnosis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... Leukemia, Tumour ... Non-lmmune: • HELLP ... Syndrome • TTP
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... Syndrome and Acute ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... Pregnancy Three syndromes ... coagulation defects. 1) HELLP ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential Diagnosis ... antiphospholipid syndrome ... - Pregnancy: HELLP ... #Framework #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... Neutropenia, anemia, thrombocytopenia ... • Richter’s Syndrome ... • Sezary syndrome ... #diagnosis #workup
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... infiltrates (anemia, thrombocytopenia ... • Tumor lysis syndrome ... #Hematology #Oncology ... #Diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Schistocytes, thrombocytopenia ... - DIC, TTP, HELLP ... #Algorithm #workup ... #hematology #testing
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... coagulation (DIC) - HELLP ... syndrome - ... microangiopathy: Thrombotic thrombocytopenic ... #hematology #anemia
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Bernard-Soulier Syndrome ... Grey Platelet Syndrome ... Platelet #Defects #comparison ... #differential #diagnosis ... #hematology