37 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hematologic: Acute blood ... Inflammatory Conditions: Rheumatologic ... Vasculitides, IBD, Celiac disease ... #Algorithm #hematology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint Pain ... parvovirus B19 infection ... Sarcoidosis #dermatology ... #differential #diagnosis ... #rheumatology
Janeway Lesions in Endocarditis seen on Physical Exam 

Dr Supradip Ghosh
@dr_supradip

36 year old male with history
Blood cultures growing ... His sister shared ... Infective Endocarditis ... could have been diagnosed ... #dermatology #soles
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
burning sensation or pain ... • Fungal infections ... vasculitis (inflamed blood ... #rash #diagnosis ... #rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Immunoglobulin M (IgM) • Blood ... sensitize red blood ... chills, flank pain ... hemolytic #anemia #hematology ... #diagnosis
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... , Drugs, Liver Disease ... Internal (RBC) - Infections ... - Peripheral Blood ... #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
Chronic kidney disease ... (e.g. cancer, infection ... G6PD deficiency), Infections ... Production #Index #hematology ... #differential #diagnosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
., HIV), EBV infection ... Alcohol-induced pain ... : Pain in involved ... Etiology: - Infections ... #differential #hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
- Differential Diagnosis ... the total white blood ... Colitis and Crohn’s Disease ... #Differential #Diagnosis ... #causes #hematology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Approach to Joint Pain ... - Diagnostic Framework ... ), RA, crystal disease ... #Joint #Pain #MSK ... #rheumatology #