769 results
Pulmonary complications of targeted therapy
-Immune checkpoint inhibitors (e.g. pembrolizumab)
-Pneumonitis is uncommon (~5% of patients) but can
Pulmonary complications ... Immune checkpoint inhibitors ... associated with a clinical ... unclear if this is a drug ... #Clinical #Diagnosis
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
necrosis factor-α inhibitors ... • Injection drug ... • HIV: 2/3 pulmonary ... characteristic features Clinical ... Treatment With TNF Inhibitor
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
necrosis factor-α inhibitors ... • Injection drug ... • HIV: 2/3 pulmonary ... characteristic features Clinical ... Treatment With TNF Inhibitor
PDE5 inhibitors are usually the drugs of first choice for erectile dysfunction.

PDE5 inhibitors enhance an erection that is
PDE5 inhibitors ... are usually the drugs ... Drug interactions ... depending on the drug ... medications #dosing #drugs
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
Drugs associated ... Antimicrobials Drug-induced ... Tyrosine kinase inhibitors ... - Calcineurin inhibitors ... panitumumab) #Drugs
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Drugs a. ... Direct Xa inhibitors ... Specific inhibitors ... Drugs a. ... drugs e.g. direct
HIV Antiretroviral Pharmacokinetic Boosters - Ritonavir & Cobicistat 

Ritonavir & Cobicistat are 2 pharmacokinetic boosters used
are both CYP3A4 INHIBITORS ... metabolism of drugs ... and a 3A4 inhibitor ... is just a 3A4 inhibitor ... both have lots of drug
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Drugs: Direct or ... indirect inhibitory ... drugs (e.g. direct ... Inhibitors: Non ... specific inhibitor
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... • Direct renin inhibitor ... Angiotensin-converting enzyme (ACE) inhibitors ... • Calcineurin Inhibitors
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
anti-coagulation drugs ... Selective factor Xa inhibitors ... thrombin (factor lla) inhibitors ... table #management #drugs