1708 results
diagnosis differential pharmacology management causes algorithm medications signs symptoms cardiology nephrology table treatment endocrinology hematology syndrome comparison clinical neurology dermatology
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... • Direct renin inhibitor ... Angiotensin-converting enzyme (ACE) inhibitors ... • Calcineurin Inhibitors ... differential #diagnosis #pathophysiology
Immune Reactions and Immunosuppressant Drugs Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2 Muromonab-CD3 - Monoclonal antibody Calcineurin
Immunosuppressant Drugs ... antibody Calcineurin inhibitors ... Immunosuppressant #Drugs ... #Pharmacology #Pathophysiology
Drugs that Impair Renal Potassium Excretion Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair ... Aldosterone Release: ACE inhibitors ... #Hyperkalemia #Pathophysiology
Euglycemic Diabetic Ketoacidosis (EuDKA) SGLT2 Inhibitors Increasing Indications Significant Adverse Drug Effects Definition of EuDKA • Metabolic acidosis with pH
(EuDKA) SGLT2 Inhibitors ... Significant Adverse Drug ... level < 200 mg/dL Pathophysiology
Drugs with Actions on Bronchial Smooth Muscle Bronchodilation is promoted by cAMP. Intracellular levels of cAMP can
Drugs with Actions ... phosphodiesterase (PDE) inhibitors ... #SmoothMuscle #Pathophysiology
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
Group A Strep - Drugs ... necrosis factor a inhibitors ... HenochScholeinPurpura #Pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... immune deficiency, Drugs ... Anti-IFN-y and JAK inhibitors
Allopurinol Pharmacology Summary Xanthine oxidase inhibitor blocking the formation of new uric acid Initiate 1-2 days prior to
Xanthine oxidase inhibitor ... hypersensitivity Drug ... #Pharmacology #pathophysiology
PDE5 inhibitors are usually the drugs of first choice for erectile dysfunction. PDE5 inhibitors enhance an erection that is
PDE5 inhibitors ... are usually the drugs ... Drug interactions ... depending on the drug ... medications #dosing #drugs
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
Drugs associated ... Antimicrobials Drug-induced ... Tyrosine kinase inhibitors ... - Calcineurin inhibitors ... panitumumab) #Drugs
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