69 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... - Differential Diagnosis ... Abnormal peripheral smear ... Hypersplenism, Infection ... #hematology
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
Anemia Intravascular ... LDH Peripheral smear ... #Anemia #Laboratory ... Testing #workup #diagnosis ... #hematology #hemolysis
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
Autoimmune Hemolytic ... Anemia (AIHA) Pathophysiology ... or negative - Smear ... C3 positive - Smear ... #diagnosis #hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Anemia 1) DIAGNOSE ... C3d • Blood smear ... #Anemia #diagnosis ... #management #treatment ... #rheumatology
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood Smear ... Microangiopathic hemolytic ... Peripheral #Blood #Smear ... #Analysis #hematology ... interpretation #clinical
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Hemolytic Anemia ... Spherocytes • Treatment ... • Treatment: Warm ... #Anemia #hematology ... #diagnosis #comparison
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... and laboratory diagnosis ... arrow) Peripheral smear ... #anemia #Hematology ... #Pathology #Smear
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... anemia): ... spherocytosis) • Infections ... #differential #diagnosis ... #hematology #anemia
Herpes Zoster: Dermatomally distributed vesicles in patient with HZV infection.

Charlie Goldberg, M.D. - UCSD Catalog of
patient with HZV infection ... Images #Clinical ... #Dermatology #SkinRash ... #Herpes #Zoster ... Vesicles #UCSDH #Photo
V2 Distribution Zoster: Patient with herpes zoster infection of the maxillary branch of the fifth cranial
infection of the ... Photo credit, Simerjot ... UCSD Catalog of Clinical ... Images #Clinical ... #Photo #Dermatology