11 results
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... Cirrhosis • Chronic ... Hepatopathy • Acute ... injury) • Ischemic ... Diagnosis #hepatology #transaminitis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Injury (DILI) ... #Chronic #Liver ... Cirrhosis #Hepatology #gastroenterology ... #management #diagnosis
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... Injury Transaminase ... > 20x normal - Acute ... 5-10x normal - Chronic ... #LFTs #transaminitis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... presentation • Chronic ... differential #Diagnosis #Management ... #gastroenterology ... #algorithm #gastroenterology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Mixed - Check Acute ... injury < 26 weeks ... > 2 • NASH, Chronic ... > 3 • Chronic ... differential #Hepatology #transaminitis
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... Torsemide) • Acute ... heart failure, liver ... hyperaldosteronism • Acute ... Excretion #Diuresis #Nephrology
Chronic Pancreatitis

Definition: A pathologic fibroinflammatory syndrome of the pancreas in individuals with genetic, environmental, and/or other
Chronic Pancreatitis ... to parenchymal injury ... EmoryGastroHep #Chronic ... Pancreatitis #diagnosis #management ... #gastroenterology
Noninvasive Positive Pressure Ventilation (NIPPV)

Expiratory & Inspiratory Positive Airway Pressure
Both increase intrathoracic pressure, which can decrease
on chronic resp ... COPD) • Other acute ... pneumothorax. esophageal injury ... #indications #criticalcare ... #management
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
subclinical disease to acute ... liver failure ... - Symptoms of chronic ... hepatocellular pattern of liver ... injury, though
Percutaneous Endoscopic Gastrostomy (PEG) Complications and Prevention
 • Cardiopulmonary events
 • Buried bumper
 • Bleeding
 •
Peritonitis • Colonic ... tumor seeding • Liver ... injury #Percutaneous ... Complications #Management ... #gastroenterology