1563 results
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
Elevation == Decreased ... Asplenia Laboratory Interference ... Reduction == Increase ... HgbA1c #Laboratory #Increase ... #Decrease #Diagnosis
COMMONLY ENCOUNTERED MEDICATIONS THAT INCREASE OR DECREASE WARFARIN’S INTERNATIONAL NORMALIZED RATIO (INR)

#Pharmacology #Warfarin #Medications #Interactions #INR
MEDICATIONS THAT INCREASE ... OR DECREASE WARFARIN ... RATIO (INR) #Pharmacology ... INR #Increases #Decreases
Pressors and Inotropes

Norepinephrine
 • alpha1 > beta 1
 • Increase SVR > Inotropy
Vasopressin
 • V1
 •
• alpha 1 • Increase ... • Inotropy > Increase ... • Inotropy, Decrease ... • Inotropy, Decrease ... #criticalcare #pharmacology
Hydroxyurea - Pathophysiology and Benefits in Sickle Cell Disease
 • Decreases number of pain crises (
Cell Disease • Decreases ... 4.5 vs. 2.4) • Decreases ... organ benefit and decreased ... pathophysiology #pharmacology
Diastolic Dysfunction Grading - Echocardiography
Grade 0  (Normal):
 • E/A >0.8, e’ > 8 cm/s, E/e’
Impaired Relaxation & Decreased ... Compliance • Mild Decrease ... /e’ 8 - 15 • Increase ... Filling • Moderate Decrease ... enlargement • Severe Decrease
Noninvasive Positive Pressure Ventilation (NIPPV)

Expiratory & Inspiratory Positive Airway Pressure
Both increase intrathoracic pressure, which can decrease
Both can decrease ... larger VT and decreases ... In CHF, decreases ... In COPD, decreases ... Cannot tolerate decreased
Pharmaceutical Management of Hyperthyroidism / Thyroid Storm
Beta-Blockers 
• Decreases sympathetic hyperactivity 
• Partially blocks peripheral conversion
Beta-Blockers • Decreases ... thyroid hormone • Decreases ... Steroids • Decrease ... ThyroidStorm #Management #Pharmacology
Medications for High-Altitude Sickness 
Acetazolarnide 
 • Carbonic Anydrase Inhibitor Bicarb diuresis & metabolic Acidosis ->
Dexamethasone • Decrease ... vasogenic edema • Decrease ... Nifedipine • Decreases
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Excretion Decreased ... , Pentamidine Decreased ... Ketoconazole Decreased ... Beta-Blockers Decreased ... Pathophysiology #Pharmacology
Auto-PEEP 
What is Auto-PEEP?
 • Progressive air trapping & dynamic hyperinflation → ↑Palv at end expiration
barotrauma and decreased ... • Decrease airway ... (Tflow rate = decrease ... I:E ratio, decrease ... RR) • Decrease