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hematology treatment anemia aplastic apml chronic cll differentiation hemophagocytic hlh leukemia leukostasis lymphocytic lymphohistiocytosis lysis mds ms multiple myelodysplasia myelodysplastic
Clinical Manifestations of Serotonin Syndrome • Ophthalmologic: Mydriasis, Ocular clonus (slow horizontal movements) • Gastrointestinal: Diarrhea,
Manifestations of Serotonin Syndrome ... sounds, RUQ pain • Dermatologic ... Hyperthermia UCSD Internal ... #Symptoms #spectrum ... #signs #diagnosis
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... Associated PNH SCVMC Internal ... #management #treatment ... #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... WBC >100k, + lab signs ... arrhythmis SCVMC Internal ... #TLS #diagnosis ... #management #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
conjunctivitis) - Internal ... Episcleritis Signs ... and Symptoms: ... #diagnosis #dermatology ... #oncology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Multiple Sclerosis Diagnosis ... Signs and symptoms ... taper 3-7 days - Short ... #management #neurology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... : >3 symptoms, or ... Differentiation #Syndrome ... #management #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... • Improve the symptoms ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... • Richter’s Syndrome ... #workup #oncology ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... : HLH signs and ... symptoms can mimic ... #management #treatment ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... age 70 years Symptoms ... Pinpoint-sized red spots ... #diagnosis #hematology ... #oncology
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