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hepatology transaminitis algorithm causes enzymes interpretation abnormal chemistry cholestatic comparison dili disorders drug elevation function functiontest gastroenterology hepatocellular hodgkins hyperferritinemia
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... • R value = (ALT ... Transaminitis #diagnosis ... #differential # ... hepatology
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
(LFTs) Elevation ... abnormality vs bone ... ALP ≥ 2x ULN R Value ... Transaminitis #diagnosis ... #hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
(LFTs) - Normal ... , bone, placenta ... Function #Tests #LFTs ... Interpretation #diagnosis ... #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... Calculate R-Value ... Idiosyncratic #differential ... gastroenterology #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... hemolysis) • ALP: Bone ... #chemistry #diagnosis ... #differential # ... #LFTs #RValue #
Causes of Hyperferritinemia - Differential Diagnosis Ferritin > 1000 Ferritin is the storage form of iron. Increased hepcidin
Diagnosis Ferritin ... be used by the bone ... is made in the liver ... HLH or Adult Onset ... Hematologic Malignancy
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... : INR/PT, aPTT(liver ... gastric bypass), LFT ... (liver disease) ... candidate) - Bone
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
aminotransferase; BMI, body ... #LFTs #Abnormal ... #Algorithm #Hepatology ... #Differential # ... Diagnosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Epidemiology: young adults ... the spleen or liver ... Diagnosis of B-Symptoms ... #differential # ... hematology
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