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management hematology differential oncology mds myelodysplastic algorithm anemia barre bradi bradycardia cardiomyopathy cd4 chf clinical criticalcare foamed gbs guillain heartfailure
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... dys- (abnormal) -plastic ... old, ~10,000 new cases ... #Management #treatment ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Bradycardia - Differential Diagnosis Framework BRADI Mnemonic • BRASH/Hyperkalemia • Reduced oxygen/Glucose/Temp • ACS • Drugs •
- Differential Diagnosis ... • Drugs • ICP ... blocking agent • Shock ... #differential #diagnosis ... #causes #cardiology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Purtilo (XLP) Acquired ... Drugs, Unknown cause ... Treatment: • ... of emergency, ICU ... #summary #rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... • Anemia • Aplastic ... Significance (ICUS ... #diagnosis #hematology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
essentially Cardiogenic Shock ... acute coronary syndrome ... the determined cause ... algorithm #management #cardiology ... #criticalcare #icu
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential Diagnosis ... hypertension and/or drug treatment ... Chediak-Higashi syndrome ... white blood cell aplasia ... #causes #hematology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
Lymphocytopenia DIAGNOSTIC ... chemotherapy) • Genetic syndromes ... Heme (lymphoma. aplasia ... #diagnosis #hematology ... #Differential #Causes
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... and cauda equina TREATMENT ... intensive care unit (ICU ... Guillain #Barre #Syndrome
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... Pts: cardiogenic shock ... Avoid ARBs • ICD ... #management #cardiology ... #treatment
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