12 results
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
Shock and Vasoactive ... Arrhythmias / CHB ... vasoactive drug pharmacology ... Vasoactive #Drugs #pharmacology ... inopressors #diagnosis #management
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Shock - Differential ... Decompensated CHF ... Dehydration Shock ... Differential #Diagnosis #criticalcare ... algorithm #treatment #management
Vasopressors and Inotropes
 • Norepinephrine - Levophed - "Levo" - Generally thought of as the first
pressor added in shock ... in refractory shock ... Vasopressors #Inotropes #management ... #criticalcare # ... comparison #table #pharmacology
Vasopressors Demystified

Shock comes in many flavors and so do vasopressors. Here’s a OnePager summarizing my approach
Demystified Shock ... Vasopressors #Basics #CriticalCare ... #Management #Pharmacology
Clinical Management for Three Common Causes of Shock 
HEMORRHAGIC SHOCK
 • Ensure adequate ventilation and oxygenation.
Clinical Management ... HEMORRHAGIC SHOCK ... • Consider intraaortic ... #Shock #Management ... #CriticalCare
Pressors and Inotropes

Norepinephrine
 • alpha1 > beta 1
 • Increase SVR > Inotropy
Vasopressin
 • V1
 •
Pressors #Inotropes #criticalcare ... #pharmacology # ... comparison #shock ... #management
Shock - Diagnosis and Management Summary
 • Hypotension: SBP<90, SBP drop >40, MAP<65 (Normotension, HTN possible
Shock - Diagnosis ... and Management ... IV's, Consider IL NS ... #Diagnosis #Management ... #Summary #criticalcare
Naloxone - Toxicology

Adult starting dose:
 - 0.4 mg IV/IM/IO/SQ for non-opioid dependent patients
 - 0.04 mg
other causes of CNS ... an infusion is required ... respiratory & CNS ... Narcan #Toxicology #Management ... #Pharmacology #
CSF Penetration of Antimicrobials

Despite the poor CSF penetration, beta-lactams have the most research documenting successful treatment
CSF Penetration ... treatment of community-acquired ... in treatment of CNS ... #Penetration #CNS ... InfectiousDiseases #Pharmacology
Diuresis in Critical Care - Achieving a Negative Fluid Balance
Advantages Of A Negative Fluid Balance:
 •
MINIMIZE INs: ... aldosterone states (CHF ... Fluid #Balance #management ... #criticalcare