48 results
Classification of Diabetes Insipidus

Central or neurogenic diabetes insipidus:
 - Congenital - Structural malformations affecting the hypothalamus
AQP-2 gene - Acquired ... uropathy, Metabolic causes ... Treatment is aimed ... Classification #Types #Nephrology ... #Diagnosis #Differential
BRASH Syndrome

B - Bradycardia
R - Renal failure
A - AV nodal blockade
S - Shock
H - Hyperkalemia

Typical ECG
blockade S - Shock ... hyperkalemia) BRASH Treatment ... • Aggressive treatment ... BRASH #Syndrome #diagnosis ... #management #pathophysiology
Streptococcal Toxic Shock Syndrome (STSS)
Complication of invasive GAS disease characterized by shock & MOF → occurs
GAS in 30% of cases ... 50% in nec fasc Diagnostic ... necrosis STSS Treatment ... Syndrome #STSS #treatment ... #management #diagnosis
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Toxic Megacolon, Shock ... Perforation) Pathophysiology ... can be community-acquired ... Ileus, Megacolon, Shock ... #management #treatment
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
Hyponatremia - Diagnosis ... Hyponatremia is usually caused ... the underlying cause ... #Treatment #management ... #nephrology #sodium
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Salicylate Toxicity - Diagnosis ... no respiratory cause ... Pulmonary edema, Shock ... Toxicity #Toxicology #diagnosis ... #management #Treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Purtilo (XLP) Acquired ... Drugs, Unknown cause ... Treatment: • ... #management #treatment
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... → Inflammation causes ... functional ID) Treatment ... endpoint of all-cause ... #management #cardiology
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
Classification Diagnosis ... inherited disease • Acquired ... cell-mediated in > 90% of cases ... Classification #Types #Diagnosis ... #Treatment #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... permeability Diagnosis ... Puncture, EEG Treatment ... #management #treatment