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management diagnosis infectiousdiseases hematology syndrome pharmacology acute nejm neurology photo pulmonary rheumatology sepsis sirs abscess activation adjuvant algorithm anemia antimicrobials
Adjuvant therapies in critical care: steroids to treat infectious diseases - Severe Community Acquired Pneumonia
Adjuvant therapies in critical ... steroids to treat infectious ... SCAP severe community-acquired ... InfectiousDiseases #Infections ... Pharmacology #Management #Treatment
Systemic Inflammatory Response Syndrome (SIRS) • Non-specific (infections vs non-infectious) • ≥2 of the following: o Temp >38°C or <36°C o HR >90 bpm o RR
Non-specific (infections ... vs non-infectious ... host response to infection ... recognition & treatment ... (within 1 hour)
Algorithm for the Evaluation of Acute Diarrhea (< 7 days) Are the following present? 1.
hospitalization or antibiotics ... Community water-borne ... HIV infection or ... Consider empiric antibiotic ... Hospitalization required
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Clostridioides Difficile Infection ... GrepMed Handbook Clinical ... nosocomial infection ... post-ABx, but can be community-acquired ... #Clostridium #Infection
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
hypogammaglobulinemia -> increased infection ... history of recurrent infections ... disease • Infectious ... frequent and severe community-acquired ... infections: Pneumonia
CSF Penetration of Antimicrobials Despite the poor CSF penetration, beta-lactams have the most research documenting successful treatment
of community-acquired ... classes. 1 only ... CNS infections ... susceptible CNS infections ... of CNS infections
Sulfonamides - Antibiotics Class Overview BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic Spectrum: Wide
choice, both for treatment ... prophylaxis), Community-acquired ... MRSA Skin infections ... Nocardiosis, Listeria infections ... patients, Salmonella infections
Sepsis - Diagnosis and Management Life-threatening organ dysfunction caused by a dysregulated host response to infection SEPTIC SHOCK
host response to infection ... SEPTIC SHOCK is ... Clinical construct ... recognition and treatment ... broad spectrum antibiotics
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
Disseminated Infections ... 50% in chronic infection ... weeks for acute infection ... forms: 1) Rhinocerebral ... fever • Septic shock
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
polymicrobial infection ... Pathophysiology: 1. ... Lung Abscess - Clinical ... hemorrhage • Treatment ... treatment until
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