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management infectiousdiseases syndrome acute differential hematology criticalcare encephalopathy gastroenterology neurology peritonitis pharmacology pulmonary rheumatology abscess activation algorithm anemia aniongap antibiotic
Causes of Antibiotic Failure - Differential Diagnosis Framework Diagnosis: • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
: • Non-Infectious ... take 48 hrs for infections ... Predisposition to Infections ... rxn), Secondary infection ... Infection: IV catheter
Common Infections in Solid-Organ Transplant Recipients < 1 Month - Infection with antimicrobial-resistant species - Donor-derived infection
Common Infections ... Recipients < 1 ... colonization) 1- ... > 6 Months - Community-acquired ... #Timeline #Diagnosis
Algorithm for the Evaluation of Acute Diarrhea (< 7 days) Are the following present? 1.
Community water-borne ... HIV infection or ... Consider empiric antibiotic ... Hospitalization required ... algorithm #workup #diagnosis
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Clostridioides Difficile Infection ... Toxic Megacolon, Shock ... nosocomial infection ... post-ABx, but can be community-acquired ... #Clostridium #Infection
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
hypogammaglobulinemia -> increased infection ... history of recurrent infections ... disease • Infectious ... frequent and severe community-acquired ... infections: Pneumonia
Streptococcal Toxic Shock Syndrome (STSS) Complication of invasive GAS disease characterized by shock & MOF → occurs
50% in nec fasc Diagnostic ... necrosis STSS Treatment ... IVIG 1g/kg on day 1, ... day 2 + 3 BIDMC Infectious ... #management #diagnosis
Sepsis - Diagnosis and Management Life-threatening organ dysfunction caused by a dysregulated host response to infection SEPTIC SHOCK
Sepsis - Diagnosis ... host response to infection ... SEPTIC SHOCK is ... recognition and treatment ... broad spectrum antibiotics
Sulfonamides - Antibiotics Class Overview BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic Spectrum: Wide
choice, both for treatment ... prophylaxis), Community-acquired ... MRSA Skin infections ... Nocardiosis, Listeria infections ... patients, Salmonella infections
CSF Penetration of Antimicrobials Despite the poor CSF penetration, beta-lactams have the most research documenting successful treatment
of community-acquired ... classes. 1 only ... in clinical CNS infections ... susceptible CNS infections ... of CNS infections
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
polymicrobial infection ... Pathophysiology: 1. ... Switch to oral antibiotics ... hemorrhage • Treatment ... treatment until
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