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management diagnosis pharmacology hematology infectiousdiseases cap idsa indications infection neurology pneumonia rheumatology sepsis sirs activation acute adjuvant algorithm anemia antibiotic
Adjuvant therapies in critical care: steroids to treat infectious diseases - Severe Community Acquired Pneumonia
steroids to treat infectious ... Acquired Pneumonia ... SCAP severe community-acquired ... respiratory distress syndrome ... Pharmacology #Management #Treatment
Antibiotic treatment durations for first line antibiotics recommended by Public Health England (PHE) guidance • Acute
Antibiotic treatment ... acquired pneumonia ... CRB65=0 7 days • Community ... acquired pneumonia ... and CRB65=1 7-10
Antibiotics for severe community-onset pneumonia Atypical coverage always - Usually azithromycin 500 mg daily - Doxycycline
severe community-onset ... piperacillin-tazobactam Septic Shock ... Hospitalization for > 1 ... - Linezolid 1 ... #Acquired #Pneumonia
Causes of Antibiotic Failure - Differential Diagnosis Framework Diagnosis: • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Causes of Antibiotic ... NMS, serotonin syndrome ... Immunocompromise Treatment ... • Secondary to Treatment ... diff) • Hospital-Acquired
Algorithm for the Evaluation of Acute Diarrhea (< 7 days) Are the following present? 1.
hospitalization or antibiotics ... Community water-borne ... HIV infection or ... Consider empiric antibiotic ... Hospitalization required
Systemic Inflammatory Response Syndrome (SIRS) • Non-specific (infections vs non-infectious) • ≥2 of the following: o Temp >38°C or <36°C o HR >90 bpm o RR
Inflammatory Response Syndrome ... Septic Shock • ... recognition & treatment ... (within 1 hour) ... Broad-spectrum antibiotics
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Affects 1:25,000 ... and 1:50,000 patients ... frequent and severe community-acquired ... : • Nephrotic syndrome ... (Epstein-Barr syndrome
Streptococcal Toxic Shock Syndrome (STSS) Complication of invasive GAS disease characterized by shock & MOF → occurs
Syndrome (STSS) ... necrosis STSS Treatment ... IVIG 1g/kg on day 1, ... day 2 + 3 BIDMC Infectious ... #Syndrome #STSS
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Toxic Megacolon, Shock ... Epidemiology: • #1 ... post-ABx, but can be community-acquired ... Ileus, Megacolon, Shock ... 10 mg/kg IV x 1
Orthopedic Emergencies Compartment Syndrome • An increase in compartment pressure to the point where tissue perfusion is
appear in 1-2 days ... • Management: 1. ... progressive inflammatory infection ... including DM • Treatment ... - Antibiotic
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